In episode " The Conference Valuation " (S12E17), the story splits between a high-stakes pharmaceutical convention in San Diego and a chaotic "science day" back in Pasadena. The Pharmaceutical Convention
Watch Penny's masterful drug-pushing pitch at the convention: [S12E17] The Conference Valuation
Back at home, Howard is left alone with the kids and invites the guys over for company. The day takes a turn when Sheldon finds a book on developmental experiments for children. In episode " The Conference Valuation " (S12E17),
Danny offers Penny a job, leading her to realize she doesn't always feel appreciated by Bernadette. Danny offers Penny a job, leading her to
Bernadette eventually fights to keep her, and Penny declines the rival offer, though Bernadette secretly keeps a napkin with Danny's high-salary offer hidden from Penny. The "Guinea Pig" Day
Sheldon and Amy use the children to test cognitive and motor skills, much to Howard's amusement and Leonard's distress.
Penny and Bernadette travel to San Diego to promote a new drug. Penny, thriving in her role as a sales lead, catches the attention of Danny, a representative from a rival company that Bernadette despises.