: De’Von Achane led the Dolphins with 128 rushing yards and two touchdowns, while the Chargers' Kimani Vidal notched his first career 100-yard rushing game. Historical Significance and "The Epic in Miami"

: The Chargers defeated the Dolphins 41–38 in double overtime. Tight end Kellen Winslow had a legendary performance, catching 13 passes for 166 yards and blocking a potential game-winning field goal while suffering from extreme exhaustion.

: Quarterback Justin Herbert escaped a sack from Jaelan Phillips to complete a 42-yard pass to Ladd McConkey, putting the Chargers in scoring range.

: Trailing 27–26 with only 46 seconds remaining after a Darren Waller touchdown, the Chargers relied on a 40-yard kickoff return from Nyheim Hines to gain field position.

: Before the 2025 win, the Dolphins had won the 2023 season opener 36–34 in a high-scoring shootout where Tua Tagovailoa threw for 466 yards.