The headline bout featured a clash between Team X member Natalia "Natsu" Karczmarczyk and Lexy Chaplin. Despite both being MMA debutants, the fight went the full distance. Natalia "Natsu" Karczmarczyk . Method: Unanimous Decision after 3 rounds. Stats & Details: Weight Class: Open Weight (around 125 lbs / 56.4–57 kg). Fight Duration: 3 rounds of 3 minutes each (9:00 total).

Medusa won by Submission (Kimura) in Round 3.

The rivalry between Lexy and Natsu did not end at High League 1. Lexy Chaplin later secured a victory in their rematch at on September 17, 2022, winning the vacant HL Flyweight Championship via unanimous decision. Expand map Lexy Chaplin vs. Natalia Karczmarczyk, High League 1