Because the protein cannot break down the analog, the G-protein remains locked in its active, bound state. Activation Mechanism: It binds directly to G-protein -subunits. 3. Key Research Applications
Guanosine 5 - g-thio triphosphate = 75 HPLC, powder 94825-44-2
Solutions are very unstable; they must be prepared immediately prior to use. g8634.mp4
Used to protect proteins from proteolytic degradation. 4. Stability and Handling The product is sensitive and requires careful handling. Storage: -20°C.
G8634 is crucial for studying cellular signaling pathways, specifically: Because the protein cannot break down the analog,
Requires a dust mask (N95), eyeshields, and gloves. WGK: 3. Source References: Sigma-Aldrich Product Detail PubMed - Cell Signaling Studies Sigma-Aldrich SDS
Here is a detailed overview based on the provided technical information. Key Research Applications Guanosine 5 - g-thio triphosphate
It is a standard reagent used to keep G-proteins in a perpetually active state during studies of kinase activity and GPCR (G-protein-coupled receptor) signaling.