Excess low-density lipoprotein cholesterol (LDL-C) infiltrates the arterial wall, leading to plaque formation and atherosclerosis.

Patients with Type 2 Diabetes often exhibit a specific triad: high triglycerides, low HDL-C, and the presence of small, dense LDL particles that are highly prone to oxidation. Updated Diagnostic and Screening Guidelines (2024–2026)

Dyslipidemia is primarily driven by either genetic (primary) or acquired (secondary) factors.

Recent updates emphasize earlier screening and refined risk stratification: