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The study highlights how losing a degron (a protein degradation signal) stabilizes the resulting fusion protein.

9,624 tumor samples from TCGA, investigating degron loss (a mechanism that stabilizes proteins, encouraging cancer growth). Key Findings: 24336.rar

If you can tell me where you saw the file "24336.rar" or provide more context on its content, I can try to give you a more specific report. The study highlights how losing a degron (a

Genetic fusions favor tumorigenesis through degron loss in oncogenes 624 tumor samples from TCGA

Fusions involving known oncogenes often retain functional domains and are "in-frame," supporting their role in cancer, as noted in the Nature Communications study .