16748mp4

The paper relies heavily on time-lapse movies to visualize these cellular dynamics. For example, Video 2 (referenced as part of eLife 16748) shows the accumulation and eventual egress of YFP- -catenin in cells treated with Wnt3a.

The team used HEK293 cells and techniques like fluorescence recovery after photobleaching (FRAP) to measure how fast proteins move within the cell. Where to Find the Paper and Videos Full Text (HTML/PDF): Available at eLife Sciences. 16748mp4

-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling" , which is identified by the digital object identifier (DOI) 10.7554/eLife.16748 . The paper relies heavily on time-lapse movies to

-catenin levels rise steadily after activation, the actual transcription of the target gene ( CCND1 ) occurs in "bursts" rather than a constant stream. 16748mp4